![WB analysis of various samples (non-reducing) using GTX20657 CD18 antibody [MEM-48]. Lane 1 : KG-1a cell lysate Lane 2 : HPB-ALL cell lysate WB analysis of various samples (non-reducing) using GTX20657 CD18 antibody [MEM-48]. Lane 1 : KG-1a cell lysate Lane 2 : HPB-ALL cell lysate](https://www.genetex.com/upload/website/prouct_img/normal/GTX20657/GTX20657_20191025_AP_001_149_w_23060620_756.webp)
WB analysis of various samples (non-reducing) using GTX20657 CD18 antibody [MEM-48]. Lane 1 : KG-1a cell lysate Lane 2 : HPB-ALL cell lysate
CD18 antibody [MEM-48]
GTX20657
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
Product group Antibodies
TargetITGB2
Overview
- SupplierGeneTex
- Product NameCD18 antibody [MEM-48]
- Delivery Days Customer9
- ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMEM-48
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3689
- Target nameITGB2
- Target descriptionintegrin subunit beta 2
- Target synonymsCD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7, integrin beta-2, cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor), complement component 3 receptor 3 and 4 subunit, complement receptor C3 beta-subunit, integrin beta chain, beta 2, integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), leukocyte cell adhesion molecule CD18, leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C
- HostMouse
- IsotypeIgG1
- Protein IDP05107
- Protein NameIntegrin beta-2
- Scientific DescriptionThis gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Tran DQ, Glass DD, Uzel G, et al. Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function. J Immunol. 2009,182(5):2929-38. doi: 10.4049/jimmunol.0803827Read this paper
- Drbal K, Angelisová P, Cerný J, et al. Human leukocytes contain a large pool of free forms of CD18. Biochem Biophys Res Commun. 2000,275(2):295-9.Read this paper
![IHC-P analysis of human spleen tissue using GTX20657 CD18 antibody [MEM-48]. IHC-P analysis of human spleen tissue using GTX20657 CD18 antibody [MEM-48].](https://www.genetex.com/upload/website/prouct_img/normal/GTX20657/GTX20657_20191025_AP_003_148_w_23060620_967.webp)


![FACS analysis of Jurkat cells using GTX15770 CD18 antibody [TS1/18] compared to an isotype control (blue). Dilution : 0.5 ug/test for 60 min at room temperature Fixation : 2% paraformaldehyde](https://www.genetex.com/upload/website/prouct_img/normal/GTX15770/GTX15770_113_FACS_w_23060620_708.webp)
![ICC/IF analysis of HL60 cells using GTX83119 CD18 antibody [10E12]. Green : CD18 Blue: DRAQ5 fluorescent DNA dye](https://www.genetex.com/upload/website/prouct_img/normal/GTX83119/GTX83119_20170912_ICCIF_1_w_23061322_504.webp)

