Bio-Connect

CD18 antibody [YFC118.3] (PE)

GTX76239
GeneTex
ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityCanine, Guinea Pig, Human
TargetITGB2
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD18 antibody [YFC118.3] (PE)
  • Delivery Days Customer
    9
  • Antibody Specificity
    Clone YFC118.3 is a strong reactivity with Leucocytes (platelets negative).
  • Application Supplier Note
    FACS: Neat. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    YFC118.3
  • Conjugate
    RPE
  • Gene ID3689
  • Target name
    ITGB2
  • Target description
    integrin subunit beta 2
  • Target synonyms
    CD18; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; integrin beta chain, beta 2; integrin beta-2; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); LAD; LCAMB; leukocyte cell adhesion molecule CD18; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; LFA-1; MAC-1; MF17; MFI7; truncated integrin beta-2
  • Host
    Rat
  • Isotype
    IgG2b
  • Protein IDP05107
  • Protein Name
    Integrin beta-2
  • Scientific Description
    This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
  • Reactivity
    Canine, Guinea Pig, Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. Sindrilaru A et al., 2011 Mar, J Clin Invest
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