Bio-Connect

CD239 antibody [BRIC221]

GTX75681
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman, Porcine
TargetBCAM
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD239 antibody [BRIC221]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody recognizes an epitope in the fourth extracellular domain of CD239 (B-CAM).
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    BRIC221
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4059
  • Target name
    BCAM
  • Target description
    basal cell adhesion molecule (Lutheran blood group)
  • Target synonyms
    AU; Auberger b antigen; basal cell adhesion molecule; basal cell adhesion molecule (Lu and Au blood groups); B-CAM cell surface glycoprotein; B-cell adhesion molecule; CD239; F8/G253 antigen; LU; Lutheran blood group variant LUGA; MSK19
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDP50895
  • Protein Name
    Basal cell adhesion molecule
  • Scientific Description
    This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
  • Reactivity
    Human, Porcine
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Increased adhesive and inflammatory properties in blood outgrowth endothelial cells from sickle cell anemia patients. Sakamoto TM et al., 2013 Nov, Microvasc Res
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