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CD252 [OX40L] (human)-muCD8 Fusion Protein (Biotin)

Research Use Only
ANC-512-030
Ancell Corporation
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    Ancell Corporation
  • Product Name
    CD252 [OX40L] (human)-muCD8 Fusion Protein (Biotin)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Conjugate
    Biotin
  • Formulation
    Liquid
  • Scientific Description
    Human CD252 (CD134L; OX40 ligand) is a type II membrane protein with homology to TNF which is expressed on activated B cells and activated endothelial cells. CD252 binds to CD134 present on activated T cells, providing a costimulatory signal. Blockade of this interaction in mouse abrogated immunological effects in several models of inflammation and rejection. CD252-muCD8 fusion protein binds to CD134 positive cells in flow cytometry. - Protein. Liquid. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). Human CD252 (CD134L; OX40 ligand) is a type II membrane protein with homology to TNF which is expressed on activated B cells and activated endothelial cells. CD252 binds to CD134 present on activated T cells, providing a costimulatory signal. Blockade of this interaction in mouse abrogated immunological effects in several models of inflammation and rejection. CD252-muCD8 fusion protein binds to CD134 positive cells in flow cytometry.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352202