CD27 antibody [O323]

GeneTex

CD27 antibody [O323]

9

*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry

Research Use Only

Monoclonal

O323

0.5 mg/ml

Unconjugated

CD27

CD27 molecule

S152, S152. LPFS2, T14, TNFRSF7, Tp55, CD27 antigen, CD27L receptor, T cell activation antigen S152, T-cell activation antigen CD27, tumor necrosis factor receptor superfamily, member 7

Mouse

IgG1

CD27 antigen

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Human, Monkey, Primate

2°C to 8°C

41116161