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ProductsBack/CD27 antibody [O323]

CD27 antibody [O323]

Research Use Only
GTX01457
GeneTex
ApplicationsFlow Cytometry
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Monkey, Primate
TargetCD27
Price on request
Packing Size
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ISO certified
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD27 antibody [O323]
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    O323
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID939
  • Target name
    CD27
  • Target description
    CD27 molecule
  • Target synonyms
    CD27 antigen; CD27L receptor; S152; S152. LPFS2; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; Tp55; tumor necrosis factor receptor superfamily, member 7
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Monkey, Primate
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Comparison of NGS and MFC Methods: Key Metrics in Multiple Myeloma MRD Assessment. Kriegsmann K et al., 2020 Aug 18, Cancers (Basel)
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  • A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model. Kreye J et al., 2020 Aug 16, bioRxiv
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  • Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target. Pierini S et al., 2020 Aug 20, JCI Insight
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  • Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART. Gantner P et al., 2020 Aug 14, Nat Commun
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  • Early ART in Acute HIV-1 Infection: Impact on the B-Cell Compartment. Badura R et al., 2020, Front Cell Infect Microbiol
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  • A 34-Marker Panel for Imaging Mass Cytometric Analysis of Human Snap-Frozen Tissue. Guo N et al., 2020, Front Immunol
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  • Sialyl-Lewis(X) Glycoantigen Is Enriched on Cells with Persistent HIV Transcription during Therapy. Colomb F et al., 2020 Aug 4, Cell Rep
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  • Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function. Gruber CN et al., 2020 Sep 15, Immunity
    Read more
  • Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes. Zhou T et al., 2020 Jul 21, SSRN
    Read more
  • Atypical memory B-cells and autoantibodies correlate with anemia during Plasmodium vivax complicated infections. Rivera-Correa J et al., 2020 Jul, PLoS Negl Trop Dis
    Read more