CD27(203.6), 0.2mg/mL [26628-22-8]

Biotium

CD27(203.6), 0.2mg/mL

9

Research Use Only

Monoclonal

203.6

0.2 mg/ml

CD27

CD27 molecule

CD27 antigen; CD27L receptor; S152; S152. LPFS2; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; Tp55; tumor necrosis factor receptor superfamily, member 7

Mouse

IgG3

CD27 antigen

Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27 (Workshop VI; Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Human, Mouse

2°C to 8°C

12352203