CD282 / TLR2(TLR2/221), CF405S conjugate, 0.1mg/mL [26628-22-8]

Biotium

CD282 / TLR2(TLR2/221), CF405S conjugate, 0.1mg/mL

9

Research Use Only

Monoclonal

TLR2/221

0.1 mg/ml

Other Conjugate

TLR2

toll like receptor 2

CD282; TIL4; toll/interleukin-1 receptor-like protein 4; toll-like receptor 2

Mouse

IgG2a

Toll-like receptor 2

This MAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Canine, Human, Monkey, Mouse

2°C to 8°C

12352203