CD284 Monoclonal Antibody
RD70430A
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityMouse, Rat
TargetTlr4
Overview
- SupplierReddot Biotech
- Product NameCD284 Monoclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2E12C8
- Concentration1.8 mg/ml
- ConjugateUnconjugated
- Gene ID21898
- Target nameTlr4
- Target descriptiontoll-like receptor 4
- Target synonymslipopolysaccharide response; Lps; Ly87; Ran/M1; Ras; Rasl2-8; Toll like receptor 4; toll-like receptor 4
- HostMouse
- IsotypeIgG
- Scientific DescriptionTLR4,also named as CD284,belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88,TIRAP and TRAF6,leading to NF-kappa-B activation,cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
- ReactivityMouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203