![CD284 / TLR4(TLR4/230), CF405S conjugate, 0.1mg/mL [26628-22-8] CD284 / TLR4(TLR4/230), CF405S conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2016/12/BNUB0230-0-1.jpg)
CD284 / TLR4(TLR4/230), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC040230
ReactivityBovine, Canine, Guinea Pig, Human, Monkey, Mouse, Porcine, Rat
Product group Antibodies
TargetTLR4
Overview
- SupplierBiotium
- Product NameCD284 / TLR4(TLR4/230), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDTLR4/230
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID7099
- Target nameTLR4
- Target descriptiontoll like receptor 4
- Target synonymsARMD10; CD284; homolog of Drosophila toll; hToll; TLR-4; TOLL; toll like receptor 4 protein; toll-like receptor 4
- HostMouse
- IsotypeIgG2a
- Protein IDO00206
- Protein NameToll-like receptor 4
- Scientific DescriptionThis MAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Canine, Guinea Pig, Human, Monkey, Mouse, Porcine, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203