Analysis of Protein Array containing more than 19,000 full-length human proteins using CD3e Mouse Monoclonal Antibody (C3e/2479). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.
CD3 epsilon antibody [C3e/2479]
GTX17865
ApplicationsWestern Blot, ELISA, Other Application
Product group Antibodies
ReactivityHuman
TargetCD3E
Overview
- SupplierGeneTex
- Product NameCD3 epsilon antibody [C3e/2479]
- Delivery Days Customer9
- Application Supplier NoteWB: 1-2microg/ml. ELISA: 2-4microg/ml (for coating). *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDC3e/2479
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID916
- Target nameCD3E
- Target descriptionCD3e molecule
- Target synonymsCD3e antigen, epsilon polypeptide (TiT3 complex); CD3e molecule, epsilon (CD3-TCR complex); CD3-epsilon; IMD18; T3E; T-cell antigen receptor complex, epsilon subunit of T3; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; TCRE
- HostMouse
- IsotypeIgG1
- Protein IDP07766
- Protein NameT-cell surface glycoprotein CD3 epsilon chain
- Scientific DescriptionThe protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203