IHC-P analysis of human lymph node, nodular sclerosing hodgkins disease tissue using GTX01872 CD30 antibody [JCM182]. Note membrane and cytoplasmic staining of the neoplastic cells, CD30: clone JCM182
CD30 antibody [JCM182]
GTX01872
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTNFRSF8
Overview
- SupplierGeneTex
- Product NameCD30 antibody [JCM182]
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDJCM182
- ConjugateUnconjugated
- Gene ID943
- Target nameTNFRSF8
- Target descriptionTNF receptor superfamily member 8
- Target synonymsCD30; CD30L receptor; cytokine receptor CD30; D1S166E; Ki-1; Ki-1 antigen; lymphocyte activation antigen CD30; tumor necrosis factor receptor superfamily member 8
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Chordin-like 1 is a novel prognostic biomarker and correlative with immune cell infiltration in lung adenocarcinoma. Deng B et al., 2022 Jan 12, Aging (Albany NY)Read more