FACS analysis of human peripheral blood lymphocytes using GTX01461-07 CD4 antibody [SK3] (APC). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.06 microg (5 microl)
FACS analysis of human peripheral blood lymphocytes using GTX01461-07 CD4 antibody [SK3] (APC). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.06 microg (5 microl)
CD4 antibody [SK3] (APC)
GTX01461-07
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman, Monkey, Primate
TargetCD4
Overview
- SupplierGeneTex
- Product NameCD4 antibody [SK3] (APC)
- Delivery Days Customer9
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSK3
- Concentration0.012 mg/ml
- ConjugateAPC
- Gene ID920
- Target nameCD4
- Target descriptionCD4 molecule
- Target synonymsCD4 antigen (p55); CD4 receptor; CD4mut; IMD79; OKT4D; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]
- ReactivityHuman, Monkey, Primate
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- IL-7 abrogates suppressive activity of human CD4+CD25+FOXP3+ regulatory T cells and allows expansion of alloreactive and autoreactive T cells. Heninger AK et al., 2012 Dec 15, J ImmunolRead more
- One-round determination of seven leukocyte subsets in rhesus macaque blood by flow cytometry. Lafont BA et al., 2000 Nov 1, CytometryRead more
- Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Yoshino N et al., 2000 Apr, Exp AnimRead more
- Thymus-dependent membrane antigens in man: inhibition of cell-mediated lympholysis by monoclonal antibodies to TH2 antigen. Evans RL et al., 1981 Jan, Proc Natl Acad Sci U S ARead more
- Epitopes of the CD4 antigen and HIV infection. Sattentau QJ et al., 1986 Nov 28, ScienceRead more