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FACS analysis of human peripheral blood lymphocytes using GTX01461-16 CD4 antibody [SK3] (PerCP). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.06 microg (5 microl)
FACS analysis of human peripheral blood lymphocytes using GTX01461-16 CD4 antibody [SK3] (PerCP). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.06 microg (5 microl)
FACS analysis of human peripheral blood lymphocytes using GTX01461-16 CD4 antibody [SK3] (PerCP). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.06 microg (5 microl)

CD4 antibody [SK3] (PerCP)

GTX01461-16
GeneTex
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman, Monkey, Primate
TargetCD4
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD4 antibody [SK3] (PerCP)
  • Delivery Days Customer
    9
  • Application Supplier Note
    FACS: 0.06 microg (5 microl) for 105-108 cells in 100 microl sample per test. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    SK3
  • Concentration
    0.012 mg/ml
  • Conjugate
    PerCP
  • Gene ID920
  • Target name
    CD4
  • Target description
    CD4 molecule
  • Target synonyms
    CD4mut, IMD79, Leu-3, OKT4D, T4, T-cell surface glycoprotein CD4, CD4 antigen (p55), CD4 receptor, T-cell surface antigen T4/Leu-3
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP01730
  • Protein Name
    T-cell surface glycoprotein CD4
  • Scientific Description
    This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]
  • Reactivity
    Human, Monkey, Primate
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Heninger AK, Theil A, Wilhelm C, et al. IL-7 abrogates suppressive activity of human CD4+CD25+FOXP3+ regulatory T cells and allows expansion of alloreactive and autoreactive T cells. J Immunol. 2012,189(12):5649-58. doi: 10.4049/jimmunol.1201286
    Read this paper
  • Lafont BA, Gloeckler L, D'Hautcourt JL, et al. One-round determination of seven leukocyte subsets in rhesus macaque blood by flow cytometry. Cytometry. 2000,41(3):193-202.
    Read this paper
  • Yoshino N, Ami Y, Terao K, et al. Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Exp Anim. 2000,49(2):97-110.
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  • Evans RL, Wall DW, Platsoucas CD, et al. Thymus-dependent membrane antigens in man: inhibition of cell-mediated lympholysis by monoclonal antibodies to TH2 antigen. Proc Natl Acad Sci U S A. 1981,78(1):544-8.
    Read this paper
  • Sattentau QJ, Dalgleish AG, Weiss RA, et al. Epitopes of the CD4 antigen and HIV infection. Science. 1986,234(4780):1120-3.
    Read this paper