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Western blot analysis of CD40: Lane 1: MWM Lane 2: ESK4 cell lysate Lane 3: Molt 4 cell lysate.
Western blot analysis of CD40: Lane 1: MWM Lane 2: ESK4 cell lysate Lane 3: Molt 4 cell lysate.
Western blot analysis of CD40: Lane 1: MWM Lane 2: ESK4 cell lysate Lane 3: Molt 4 cell lysate.

CD40 antibody

GTX13545
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityCanine, Guinea Pig, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Sheep
TargetCD40
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD40 antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    The antibody specificity is confirmed by specific peptide inhibition in immunoblotting studies.
  • Application Supplier Note
    Recommended dilutions: WB: 1/1000. Detects a band of approximately 45 kDa (predicted molecular weight: 34 kDa). Optimal dilutions/concentrations should be determined by the end user.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID958
  • Target name
    CD40
  • Target description
    CD40 molecule
  • Target synonyms
    B cell surface antigen CD40; B cell-associated molecule; Bp50; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDW40; p50; TNFRSF5; tumor necrosis factor receptor superfamily member 5
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP25942
  • Protein Name
    Tumor necrosis factor receptor superfamily member 5
  • Scientific Description
    This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2014]
  • Reactivity
    Canine, Guinea Pig, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Sheep
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203