CD44 antibody [IM7] (Biotin)

GeneTex

CD44 antibody [IM7] (Biotin)

9

Recognizes all isoforms of the Pgp-1 cell surface glycoprotein. The CD44 is present on B-cells, monocytes, macrophages and certain subsets of thymocytes and peripheral T-cells. Mice with the Ly-24.1 allotype have high densities of CD44+ T-cells, while Ly-

FACS: Use 1microg for 10^6 cells. IHC-Fr (acetone fixed): Use at an assay dependent dilution. IP: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.

Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

IM7

0.5 mg/ml

Biotin

Liquid

CD44

CD44 molecule (Indian blood group)

CD44 antigen; CDW44; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECMR-III; epican; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; Hermes antigen; homing function and Indian blood group system; HUTCH-I; hyaluronate receptor; IN; Indian blood group antigen; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; phagocytic glycoprotein 1; soluble CD44

Rat

IgG2b

CD44 antigen

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]

Bovine, Canine, Equine, Feline, Human, Porcine

2°C to 8°C

12352203