CD45RA Antibody (Leukocyte marker)

Biorbyt

CD45RA Antibody (Leukocyte marker)

16

Titering of the anti-CD45RA antibody may be required for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Western blot: 1-2ug/ml,Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 1-2 ug/ml,Immunohistology (FFPE): 0.5-1.0ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) FACS, IF, IHC, WB

Research Use Only

Monoclonal

CDLA45RA-1

Unconjugated

PTPRC

protein tyrosine phosphatase receptor type C

B220, CD45, CD45R, GP180, IMD105, L-CA, LCA, LY5, T200, receptor-type tyrosine-protein phosphatase C, CD45 antigen, T200 glycoprotein, T200 leukocyte common antigen, glycoprotein 180, protein tyrosine phosphatase, receptor type, c polypeptide

Mouse

IgG2a

Receptor-type tyrosine-protein phosphatase C

CD45RA is an isoform of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells.

Human

-20°C,2°C to 8°C

12352203