CD46 Polyclonal Antibody

Reddot Biotech

CD46 Polyclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

Polyclonal

2 mg/ml

Unconjugated

CD46

CD46 molecule

AHUS2, MCP, MIC10, TLX, TRA2.10, membrane cofactor protein, CD46 antigen, complement regulatory protein, CD46 molecule, complement regulatory protein, antigen identified by monoclonal antibody TRA-2-10, complement membrane cofactor protein, measles virus receptor, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), trophoblast leucocyte common antigen, trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen

Rabbit

IgG

Acts as a cofactor for complement factor I,a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells.T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

-20°C

12352203