CD55 antibody [N1C2]
GTX113170
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman
TargetCD55
Overview
- SupplierGeneTex
- Product NameCD55 antibody [N1C2]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.86 mg/ml
- ConjugateUnconjugated
- Gene ID1604
- Target nameCD55
- Target descriptionCD55 molecule (Cromer blood group)
- Target synonymsCD55 antigen; CD55 molecule, decay accelerating factor for complement (Cromer blood group); CHAPLE; complement decay-accelerating factor; CR; CROM; Cromer blood group antigen; DAF; Rh blood group D antigen; TC
- HostRabbit
- IsotypeIgG
- Protein IDP08174
- Protein NameComplement decay-accelerating factor
- Scientific DescriptionThis gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1. Tsou PS et al., 2022 Jun 1, J Clin InvestRead more
- Differential Expression of Complement Markers in Normal and AMD Transmitochondrial Cybrids. Nashine S et al., 2016, PLoS OneRead more
- Expression of human decay-accelerating factor on intestinal epithelium of transgenic mice does not facilitate infection by the enteral route. Pan J et al., 2015 Apr, J VirolRead more