Bio-Connect

CD55 antibody [N1C2]

GTX113170
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman
TargetCD55
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    CD55 antibody [N1C2]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.86 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1604
  • Target name
    CD55
  • Target description
    CD55 molecule (Cromer blood group)
  • Target synonyms
    CD55 antigen; CD55 molecule, decay accelerating factor for complement (Cromer blood group); CHAPLE; complement decay-accelerating factor; CR; CROM; Cromer blood group antigen; DAF; Rh blood group D antigen; TC
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP08174
  • Protein Name
    Complement decay-accelerating factor
  • Scientific Description
    This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1. Tsou PS et al., 2022 Jun 1, J Clin Invest
    Read more
  • Differential Expression of Complement Markers in Normal and AMD Transmitochondrial Cybrids. Nashine S et al., 2016, PLoS One
    Read more
  • Expression of human decay-accelerating factor on intestinal epithelium of transgenic mice does not facilitate infection by the enteral route. Pan J et al., 2015 Apr, J Virol
    Read more