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CD70(BU69), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC040187
Biotium
ApplicationsFunctional Assay, Flow Cytometry
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetCD70
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Overview

  • Supplier
    Biotium
  • Product Name
    CD70(BU69), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Functional Assay, Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    BU69
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID970
  • Target name
    CD70
  • Target description
    CD70 molecule
  • Target synonyms
    CD27 ligand; CD27L; CD27-L; CD27LG; CD70 antigen; Ki-24 antigen; LPFS3; surface antigen CD70; TNFSF7; TNLG8A; tumor necrosis factor ligand 8A; tumor necrosis factor ligand superfamily member 7
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP32970
  • Protein Name
    CD70 antigen
  • Scientific Description
    This antibody recognizes a protein of 30 kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown toinhibit T cell proliferation induced by dendritic cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203