FACS analysis of Raji cells using GTX34551 CD74 antibody [LN-2]. Blue : Primary antibody Red : Isotype control
![ICC/IF analysis of Raji cells using GTX34551 CD74 antibody [LN-2]. Green : Primary antibody Red : nucleus](https://www.genetex.com/upload/website/prouct_img/normal/GTX34551/GTX34551_20200115_ICC-IF_1797_w_23060801_364.webp "ICC/IF analysis of Raji cells using GTX34551 CD74 antibody [LN-2]. Green : Primary antibody Red : nucleus")
![IHC-P analysis of human spleen tissue using GTX34551 CD74 antibody [LN-2].](https://www.genetex.com/upload/website/prouct_img/normal/GTX34551/GTX34551_20200115_IHC-P_1168_w_23060801_481.webp "IHC-P analysis of human spleen tissue using GTX34551 CD74 antibody [LN-2].")
![IHC-P analysis of human tonsil tissue using GTX34551 CD74 antibody [LN-2].](https://www.genetex.com/upload/website/prouct_img/normal/GTX34551/GTX34551_20200115_IHC-P_1339_w_23060801_523.webp "IHC-P analysis of human tonsil tissue using GTX34551 CD74 antibody [LN-2].")
FACS analysis of Raji cells using GTX34551 CD74 antibody [LN-2]. Blue : Primary antibody Red : Isotype control
CD74 antibody [LN-2]
GTX34551
ApplicationsFunctional Assay, Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Primate
TargetCD74
Overview
- SupplierGeneTex
- Product NameCD74 antibody [LN-2]
- Delivery Days Customer9
- Antibody SpecificityWe do not recommend use of this product for Rat.
- Application Supplier NoteICC/IF: 1-4microg/ml. IHC-P: 1-2microg/ml for 30 minutes at RT. FACS: 1-2microg/106 cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFunctional Assay, Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDLN-2
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID972
- Target nameCD74
- Target descriptionCD74 molecule
- Target synonymsCD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule, major histocompatibility complex, class II invariant chain; DHLAG; gamma chain of class II antigens; HLA class II histocompatibility antigen gamma chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; Ia-associated invariant chain; Ia-GAMMA; II; MHC HLA-DR gamma chain; p33
- HostMouse
- IsotypeIgG1
- Protein IDP04233
- Protein NameHLA class II histocompatibility antigen gamma chain
- Scientific DescriptionThe protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
- ReactivityHuman, Mouse, Primate
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Tissue Inhibitor of Metalloproteinases-1 Interacts with CD74 to Promote AKT Signaling, Monocyte Recruitment Responses, and Vascular Smooth Muscle Cell Proliferation.Read more
- CD74 interferes with the expression of fas receptor on the surface of lymphoma cells.Read more
- Expression of CD74, the receptor for macrophage migration inhibitory factor, in non-small cell lung cancer.Read more