CD86 antibody [BU63]

GeneTex

CD86 antibody [BU63]

9

IHC-Fr: 1/20-1/100. FCM: 1/20-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

BU63

1 mg/ml

Unconjugated

CD86

CD86 molecule

B7-2, B7.2, B70, CD28LG2, LAB72, T-lymphocyte activation antigen CD86, B-lymphocyte activation antigen B7-2, BU63, CD86 antigen (CD28 antigen ligand 2, B7-2 antigen), CD86 v6, CTLA-4 counter-receptor B7.2, FUN-1

Mouse

IgG1

T-lymphocyte activation antigen CD86

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]

Human

-20°C or -80°C,2°C to 8°C

41116161