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CD86 antibody [BU63] (Low Endotoxin)

Research Use Only
GTX00600-00
GeneTex
ApplicationsFunctional Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman
TargetCD86
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD86 antibody [BU63] (Low Endotoxin)
  • Delivery Days Customer
    9
  • Applications
    Functional Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    BU63
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID942
  • Target name
    CD86
  • Target description
    CD86 molecule
  • Target synonyms
    B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28LG2; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CTLA-4 counter-receptor B7.2; FUN-1; LAB72; T-lymphocyte activation antigen CD86
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP42081
  • Protein Name
    T-lymphocyte activation antigen CD86
  • Scientific Description
    This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Impact of Isolation Procedures on the Development of a Preclinical Synovial Fibroblasts/Macrophages in an In Vitro Model of Osteoarthritis. Manferdini C et al., 2020 Dec 10, Biology (Basel)
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  • NLRP7 Is Involved in the Differentiation of the Decidual Macrophages. Tsai PY et al., 2019 Nov 28, Int J Mol Sci
    Read more
  • Serum levels of osteopontin predict major adverse cardiovascular events in patients with severe carotid artery stenosis. Carbone F et al., 2018 Mar 15, Int J Cardiol
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  • Intestine-Specific Homeobox Gene ISX Integrates IL6 Signaling, Tryptophan Catabolism, and Immune Suppression. Wang LT et al., 2017 Aug 1, Cancer Res
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  • Sunburn cell formation, dendritic cell migration, and immunomodulatory factor production after solar-simulated irradiation of sunscreen-treated human skin explants in vitro. Hofmann-Wellenhof R et al., 2004 Oct, J Invest Dermatol
    Read more