CD86 antibody [BU63] (Low Endotoxin)
GTX00600-00
ApplicationsFunctional Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
TargetCD86
Overview
- SupplierGeneTex
- Product NameCD86 antibody [BU63] (Low Endotoxin)
- Delivery Days Customer9
- ApplicationsFunctional Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDBU63
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID942
- Target nameCD86
- Target descriptionCD86 molecule
- Target synonymsB7-2, B7.2, B70, CD28LG2, LAB72, T-lymphocyte activation antigen CD86, B-lymphocyte activation antigen B7-2, BU63, CD86 antigen (CD28 antigen ligand 2, B7-2 antigen), CD86 v6, CTLA-4 counter-receptor B7.2, FUN-1
- HostMouse
- IsotypeIgG1
- Protein IDP42081
- Protein NameT-lymphocyte activation antigen CD86
- Scientific DescriptionThis gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Manferdini C, Saleh Y, Dolzani P, et al. Impact of Isolation Procedures on the Development of a Preclinical Synovial Fibroblasts/Macrophages in an In Vitro Model of Osteoarthritis. Biology (Basel). 2020,9(12). doi: 10.3390/biology9120459Read this paper
- Tsai PY, Chen KR, Li YC, et al. NLRP7 Is Involved in the Differentiation of the Decidual Macrophages. Int J Mol Sci. 2019,20(23). doi: 10.3390/ijms20235994Read this paper
- Carbone F, Rigamonti F, Burger F, et al. Serum levels of osteopontin predict major adverse cardiovascular events in patients with severe carotid artery stenosis. Int J Cardiol. 2018,255:195-199. doi: 10.1016/j.ijcard.2018.01.008Read this paper
- Wang LT, Chiou SS, Chai CY, et al. Intestine-Specific Homeobox Gene ISX Integrates IL6 Signaling, Tryptophan Catabolism, and Immune Suppression. Cancer Res. 2017,77(15):4065-4077. doi: 10.1158/0008-5472.CAN-17-0090Read this paper
- Hofmann-Wellenhof R, Smolle J, Roschger A, et al. Sunburn cell formation, dendritic cell migration, and immunomodulatory factor production after solar-simulated irradiation of sunscreen-treated human skin explants in vitro. J Invest Dermatol. 2004,123(4):781-7.Read this paper
![WB analysis of L1210 (1) and MOLT-4 (2) cell lysate using GTX82769 CD86 antibody [1B3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX82769/GTX82769_20170912_WB_w_23051501_934.webp)
![ICC/IF analysis of Ramos cells using GTX34570 CD86 antibody [SPM600]. Green : Primary antibody Red : nucleus](https://www.genetex.com/upload/website/prouct_img/normal/GTX34570/GTX34570_20200115_ICC-IF_1807_w_23060801_567.webp)


