CD86 antibody [SPM600]

GeneTex

CD86 antibody [SPM600]

9

ICC/IF: 1-2microg/ml. IHC-P: 2-4microg/ml for 30 minutes at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

SPM600

0.2 mg/ml

Unconjugated

CD86

CD86 molecule

B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28LG2; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CTLA-4 counter-receptor B7.2; FUN-1; LAB72; T-lymphocyte activation antigen CD86

Mouse

IgG1

T-lymphocyte activation antigen CD86

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203