CDC25A antibody
GTX102308
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCDC25A
Overview
- SupplierGeneTex
- Product NameCDC25A antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID993
- Target nameCDC25A
- Target descriptioncell division cycle 25A
- Target synonymsCDC25 homolog A; CDC25A2; dual specificity phosphatase CDC25A; M-phase inducer phosphatase 1
- HostRabbit
- IsotypeIgG
- Protein IDP30304
- Protein NameM-phase inducer phosphatase 1
- Scientific DescriptionCDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Elevation of soluble guanylate cyclase suppresses proliferation and survival of human breast cancer cells. Wen HC et al., 2015, PLoS OneRead more
- N-Hydroxycinnamide derivatives of osthole presenting genotoxicity and cytotoxicity against human colon adenocarcinoma cells in vitro and in vivo. Liu LY et al., 2013 Nov 18, Chem Res ToxicolRead more