
IHC-P analysis of human breast carcinoma tissue using GTX86031 CDC25A (phospho Ser178) antibody. The picture on the right is blocked with the synthesized peptide.
CDC25A (phospho Ser178) antibody
GTX86031
Overview
- SupplierGeneTex
- Product NameCDC25A (phospho Ser178) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500~1:1000. IHC-P: 1:50~1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- FormulationLiquid
- Gene ID993
- Target nameCDC25A
- Target descriptioncell division cycle 25A
- Target synonymsCDC25 homolog A; CDC25A2; dual specificity phosphatase CDC25A; M-phase inducer phosphatase 1
- Modification TypePhosphorylated
- Protein IDP30304
- Protein NameM-phase inducer phosphatase 1
- Scientific DescriptionCDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203