CDC25C antibody
GTX102809
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCDC25C
Overview
- SupplierGeneTex
- Product NameCDC25C antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.63 mg/ml
- ConjugateUnconjugated
- Gene ID995
- Target nameCDC25C
- Target descriptioncell division cycle 25C
- Target synonymsCDC25; CDC25 homolog C; dual specificity phosphatase CDC25C; mitosis inducer CDC25; M-phase inducer phosphatase 3; phosphotyrosine phosphatase; PPP1R60; protein phosphatase 1, regulatory subunit 60
- HostRabbit
- IsotypeIgG
- Protein IDP30307
- Protein NameM-phase inducer phosphatase 3
- Scientific DescriptionThis gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Melissa officinalis Extract Induces Apoptosis and Inhibits Migration in Human Colorectal Cancer Cells. Kuo TT et al., 2020 Dec 15, ACS OmegaRead more
- Macrophage Migration Inhibitory Factor Acts as the Potential Target of a Newly Synthesized Compound, 1-(9-methyl-3-carbazole)-3, 4-dihydro-beta-carboline. Ko PH et al., 2019 Feb 14, Sci RepRead more
- Differential Pharmacological Activities of Oxygen Numbers on the Sulfoxide Moiety of Wasabi Compound 6-(Methylsulfinyl) Hexyl Isothiocyanate in Human Oral Cancer Cells. Lee MJ et al., 2018 Sep 21, MoleculesRead more
- Integrating transcriptomics and proteomics to show that tanshinone IIA suppresses cell growth by blocking glucose metabolism in gastric cancer cells. Lin LL et al., 2015 Feb 5, BMC GenomicsRead more
- Quantitative proteomics reveals middle infrared radiation-interfered networks in breast cancer cells. Chang HY et al., 2015 Feb 6, J Proteome ResRead more
- Combination therapy targeting ectopic ATP synthase and 26S proteasome induces ER stress in breast cancer cells. Chang HY et al., 2014 Nov 27, Cell Death DisRead more
- N-Hydroxycinnamide derivatives of osthole presenting genotoxicity and cytotoxicity against human colon adenocarcinoma cells in vitro and in vivo. Liu LY et al., 2013 Nov 18, Chem Res ToxicolRead more
- Polo-like kinase inhibitor Ro5203280 has potent antitumor activity in nasopharyngeal carcinoma. Cheung AK et al., 2013 Aug, Mol Cancer TherRead more
- Middle infrared radiation induces G2/M cell cycle arrest in A549 lung cancer cells. Chang HY et al., 2013, PLoS OneRead more