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CDC25C antibody

Name: CDC25C antibody
SKU: GTX102809_G10
Availability: BackOrder

GTX102809

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetCDC25C

Overview

Supplier
GeneTex
Product Name
CDC25C antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.63 mg/ml
Conjugate
Unconjugated
Gene ID995
Target name
CDC25C
Target description
cell division cycle 25C
Target synonyms
CDC25, PPP1R60, M-phase inducer phosphatase 3, CDC25 homolog C, dual specificity phosphatase CDC25C, mitosis inducer CDC25, phosphotyrosine phosphatase, protein phosphatase 1, regulatory subunit 60
Host
Rabbit
Isotype
IgG
Protein IDP30307
Protein Name
M-phase inducer phosphatase 3
Scientific Description
This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Kuo TT, Chang HY, Chen TY, et al. Melissa officinalis Extract Induces Apoptosis and Inhibits Migration in Human Colorectal Cancer Cells. ACS Omega. 2020,5(49):31792-31800. doi: 10.1021/acsomega.0c04489
Read this paper
Ko PH, Shen YC, Murugan K, et al. Macrophage Migration Inhibitory Factor Acts as the Potential Target of a Newly Synthesized Compound, 1-(9'-methyl-3'-carbazole)-3, 4-dihydro-β-carboline. Sci Rep. 2019,9(1):2147. doi: 10.1038/s41598-019-38590-y
Read this paper
Lee MJ, Tseng WS, Lai JC, et al. Differential Pharmacological Activities of Oxygen Numbers on the Sulfoxide Moiety of Wasabi Compound 6-(Methylsulfinyl) Hexyl Isothiocyanate in Human Oral Cancer Cells. Molecules. 2018,23(10). doi: 10.3390/molecules23102427
Read this paper
Lin LL, Hsia CR, Hsu CL, et al. Integrating transcriptomics and proteomics to show that tanshinone IIA suppresses cell growth by blocking glucose metabolism in gastric cancer cells. BMC Genomics. 2015,16(1):41. doi: 10.1186/s12864-015-1230-0
Read this paper
Chang HY, Li MH, Huang TC, et al. Quantitative proteomics reveals middle infrared radiation-interfered networks in breast cancer cells. J Proteome Res. 2015,14(2):1250-62. doi: 10.1021/pr5011873
Read this paper
Chang HY, Huang TC, Chen NN, et al. Combination therapy targeting ectopic ATP synthase and 26S proteasome induces ER stress in breast cancer cells. Cell Death Dis. 2014,5(11):e1540. doi: 10.1038/cddis.2014.504
Read this paper
Liu LY, Huang WJ, Lin RJ, et al. N-Hydroxycinnamide derivatives of osthole presenting genotoxicity and cytotoxicity against human colon adenocarcinoma cells in vitro and in vivo. Chem Res Toxicol. 2013,26(11):1683-91. doi: 10.1021/tx400271n
Read this paper
Cheung AK, Ip JC, Lung HL, et al. Polo-like kinase inhibitor Ro5203280 has potent antitumor activity in nasopharyngeal carcinoma. Mol Cancer Ther. 2013,12(8):1393-401. doi: 10.1158/1535-7163.MCT-12-1219
Read this paper
Chang HY, Shih MH, Huang HC, et al. Middle infrared radiation induces G2/M cell cycle arrest in A549 lung cancer cells. PLoS One. 2013,8(1):e54117. doi: 10.1371/journal.pone.0054117
Read this paper

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CDC25C antibody

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