Cdk1 / p34cdc2 Serine-Threonine Kinase(A17.1.1), 1mg/mL [26628-22-8]

Biotium

Cdk1 / p34cdc2 Serine-Threonine Kinase(A17.1.1), 1mg/mL [26628-22-8]

9

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

26628-22-8

Research Use Only

Monoclonal

A17.1.1

1 mg/ml

CDK1

cyclin dependent kinase 1

CDC2, CDC28A, P34CDC2, cyclin-dependent kinase 1, cell cycle controller CDC2, cell division control protein 2 homolog, cell division cycle 2, G1 to S and G2 to M, cell division protein kinase 1, p34 protein kinase

Mouse

IgG2a

Cyclin-dependent kinase 1

Recognizes a 34 kDa protein (cdk1), identified as p34cdc2 (a catalytic subunit of Maturation Promoting Factor). Its epitope maps near the C-terminus of the protein and its core is thought to be LGTPNNEV (aa220-227 in murine cdc2). It shows no cross reaction with cdk2 p32. It supports the kinase activity. p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is a serine/threonine kinase, which is activated by cyclin, by dephosphorylation of tyrosine residues. p34cdc2 is inactivated by a tyrosine kinase. This MAb reportedly inhibits the activation of p34cdc2 kinase by cyclins. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Chicken, Guinea Pig, Human, Mammals, Mouse, Rat, Xenopus

-20°C

41116161