CDK13 Antibody

Cusabio

CDK13 Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

CDK13

cyclin dependent kinase 13

CDC2L, CDC2L5, CHDFIDD, CHED, hCDK13, cyclin-dependent kinase 13, CDC2-related protein kinase 5, cell division cycle 2-like protein kinase 5, cell division protein kinase 13, cholinesterase-related cell division controller

Rabbit

IgG

Cyclin-dependent kinase 13

Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at Lys-50 and Lys-51, thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.

Human

-20°C or -80°C

41116161