CDK2 (phospho Tyr15) antibody
GTX132802
Overview
- SupplierGeneTex
- Product NameCDK2 (phospho Tyr15) antibody
- Delivery Days Customer9
- Antibody SpecificityBased on sequence homology, this antibody may cross react with CDK1 (CDC2), CDK3, and CDK5 proteins when phosphorylated at tyrosine 15.
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.39 mg/ml
- ConjugateUnconjugated
- Gene ID1017
- Target nameCDK2
- Target descriptioncyclin dependent kinase 2
- Target synonymscdc2-related protein kinase; CDKN2; cell division protein kinase 2; cyclin-dependent kinase 2; p33 protein kinase; p33(CDK2)
- HostRabbit
- IsotypeIgG
- Protein IDP24941
- Protein NameCyclin-dependent kinase 2
- Scientific DescriptionThe protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- G2 checkpoint targeting via Wee1 inhibition radiosensitizes EGFRvIII-positive glioblastoma cells.Read more