IHC image of CSB-PA005064LA01HU diluted at 1:600 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CDK3 Antibody

CSB-PA005064LA01HU

ApplicationsELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetCDK3

Overview

Supplier
Cusabio
Product Name
CDK3 Antibody
Delivery Days Customer
20
Applications
ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID1018
Target name
CDK3
Target description
cyclin dependent kinase 3
Target synonyms
cell division protein kinase 3; cyclin-dependent kinase 3
Host
Rabbit
Isotype
IgG
Protein IDQ00526
Protein Name
Cyclin-dependent kinase 3
Scientific Description
Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

CDK3 Antibody

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Overview

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