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CDK7 antibody

GTX111919
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCDK7
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Overview

  • Supplier
    GeneTex
  • Product Name
    CDK7 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.26 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1022
  • Target name
    CDK7
  • Target description
    cyclin dependent kinase 7
  • Target synonyms
    CAK, CAK1, CDKN7, HCAK, MO15, STK1, p39MO15, cyclin-dependent kinase 7, 39 KDa protein kinase, CDK-activating kinase 1, TFIIH basal transcription factor complex kinase subunit, cell division protein kinase 7, cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase), homolog of Xenopus MO15 Cdk-activating kinase, kinase subunit of CAK, serine/threonine kinase stk1, serine/threonine protein kinase 1, serine/threonine protein kinase MO15
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP50613
  • Protein Name
    Cyclin-dependent kinase 7
  • Scientific Description
    The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • A high-throughput pipeline for validation of antibodies. Sikorski K et al., 2018 Nov, Nat Methods
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  • Regulation of Transcription Elongation by the XPG-TFIIH Complex Is Implicated in Cockayne Syndrome. Narita T et al., 2015 Sep, Mol Cell Biol
    Read more