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Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CDKN2AIP Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CDKN2AIP Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CDKN2AIP Polyclonal Antibody at dilution 1:40

CDKN2AIP Polyclonal Antibody

E-AB-10510
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    CDKN2AIP Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA IHC
  • Certification
    Research Use Only
  • Concentration
    0.3mg/ml
  • Scientific Description
    CDKN2AIP (CDKN2A-interacting protein), also known as CARF, is a 580 amino acid protein that activates p53 via p14 ARF (alternate reading frame)-dependent and independent pathways. CDKN2AIP-dependent activation of p53, a protein that up-regulates growth arrest and apoptosis-related genes in response to stress signals, leads to an enhancement of p53 function. Expression levels of CDKN2AIP and p53 show an inverse relationship that is caused by a negative-feedback control via a proteasome-mediated degradation pathway. CDKN2AIP is expressed ubiquitously across tissue samples and, along with p14 ARF, is localized to the perinucleolar region within the nucleus.
  • UNSPSC
    12352203

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