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ProductsBack/CDKN2AIP Polyclonal Antibody

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CDKN2AIP Polyclonal Antibody at dilution 1:40

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CDKN2AIP Polyclonal Antibody at dilution 1:40

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CDKN2AIP Polyclonal Antibody at dilution 1:40

CDKN2AIP Polyclonal Antibody

E-AB-10510

ApplicationsImmunoHistoChemistry

Product group Antibodies

TargetCDKN2AIP

Overview

Supplier
Elabscience
Product Name
CDKN2AIP Polyclonal Antibody
Delivery Days Customer
12
Applications
ImmunoHistoChemistry
Applications Supplier
ELISA IHC
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.3 mg/ml
Conjugate
Unconjugated
Gene ID55602
Target name
CDKN2AIP
Target description
CDKN2A interacting protein
Target synonyms
CDKN2A-interacting protein, collaborates/cooperates with ARF (alternate reading frame) protein, collaborator of ARF
Host
Rabbit
Isotype
IgG
Protein IDQ9NXV6
Protein Name
CDKN2A-interacting protein
Scientific Description
CDKN2AIP (CDKN2A-interacting protein), also known as CARF, is a 580 amino acid protein that activates p53 via p14 ARF (alternate reading frame)-dependent and independent pathways. CDKN2AIP-dependent activation of p53, a protein that up-regulates growth arrest and apoptosis-related genes in response to stress signals, leads to an enhancement of p53 function. Expression levels of CDKN2AIP and p53 show an inverse relationship that is caused by a negative-feedback control via a proteasome-mediated degradation pathway. CDKN2AIP is expressed ubiquitously across tissue samples and, along with p14 ARF, is localized to the perinucleolar region within the nucleus.
Storage Instruction
-20°C
UNSPSC
41116161

MSDS

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