Bio-Connect

C/EBP alpha antibody [N1], N-term

GTX100674
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Sheep
TargetCEBPA
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Overview

  • Supplier
    GeneTex
  • Product Name
    C/EBP alpha antibody [N1], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.59 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1050
  • Target name
    CEBPA
  • Target description
    CCAAT enhancer binding protein alpha
  • Target synonyms
    C/EBP-alpha, CEBP, CCAAT/enhancer-binding protein alpha, CCAAT/enhancer binding protein (C/EBP), alpha
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP49715
  • Protein Name
    CCAAT/enhancer-binding protein alpha
  • Scientific Description
    The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Sheep
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Yang H, Ma C, Zi Y, et al. Effects of maternal undernutrition during late pregnancy on the regulatory factors involved in growth and development in ovine fetal perirenal brown adipose tissue. Anim Biosci. 2022,35(7):1010-1020. doi: 10.5713/ab.21.0199
    Read this paper
  • Liu H, Zhan YL, Luo GJ, et al. Liraglutide and Insulin Have Contrary Effects on Adipogenesis of Human Adipose-Derived Stem Cells via Wnt Pathway. Diabetes Metab Syndr Obes. 2020,13:3075-3087. doi: 10.2147/DMSO.S253097
    Read this paper
  • Chen CC, Lee TY, Leu YL, et al. Pigment epithelium-derived factor inhibits adipogenesis in 3T3-L1 adipocytes and protects against high-fat diet-induced obesity and metabolic disorders in mice. Transl Res. 2019,210:26-42. doi: 10.1016/j.trsl.2019.04.006
    Read this paper
  • de Kerckhove M, Tanaka K, Umehara T, et al. Targeting miR-223 in neutrophils enhances the clearance of Staphylococcus aureus in infected wounds. EMBO Mol Med. 2018,10(10). doi: 10.15252/emmm.201809024
    Read this paper
  • Wu JS, Kao MH, Tsai HD, et al. Clinacanthus nutans Mitigates Neuronal Apoptosis and Ischemic Brain Damage Through Augmenting the C/EBPβ-Driven PPAR-γ Transcription. Mol Neurobiol. 2018,55(7):5425-5438. doi: 10.1007/s12035-017-0776-z
    Read this paper
  • Chen WC, Tseng CK, Chen YH, et al. HCV NS5A Up-Regulates COX-2 Expression via IL-8-Mediated Activation of the ERK/JNK MAPK Pathway. PLoS One. 2015,10(7):e0133264. doi: 10.1371/journal.pone.0133264
    Read this paper
  • Chen YF, Chong CL, Wu YC, et al. Doxorubicin Activates Hepatitis B Virus Replication by Elevation of p21 (Waf1/Cip1) and C/EBPα Expression. PLoS One. 2015,10(6):e0131743. doi: 10.1371/journal.pone.0131743
    Read this paper