C/EBP beta antibody
GTX100675
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCEBPB
Overview
- SupplierGeneTex
- Product NameC/EBP beta antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.05 mg/ml
- ConjugateUnconjugated
- Gene ID1051
- Target nameCEBPB
- Target descriptionCCAAT enhancer binding protein beta
- Target synonymsC/EBP-beta; CCAAT/enhancer binding protein (C/EBP), beta; CCAAT/enhancer-binding protein beta; IL6DBP; interleukin 6-dependent DNA-binding protein; NF-IL6; nuclear factor NF-IL6; nuclear factor of interleukin 6; TCF5; transcription factor 5; transcription factor C/EBP beta
- HostRabbit
- IsotypeIgG
- Protein IDP17676
- Protein NameCCAAT/enhancer-binding protein beta
- Scientific DescriptionThe protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- C/EBP-Family Redundancy Determines Patient Survival and Lymph Node Involvement in PDAC.Read more
- Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2. Zhao H et al., 2022 Jan 25, Cell RepRead more
- NSP2 Is Important for Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus to Trigger High Fever-Related COX-2-PGE2 Pathway in Pigs. Du L et al., 2021, Front ImmunolRead more
- Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy. Bastola S et al., 2020 Sep 16, Nat CommunRead more
- Lobohedleolide suppresses hepatitis C virus replication via JNK/c-Jun-C/EBP-mediated down-regulation of cyclooxygenase-2 expression. Lin CK et al., 2018 Jun 6, Sci RepRead more
- Downregulation of TNIP1 Expression Leads to Increased Proliferation of Human Keratinocytes and Severer Psoriasis-Like Conditions in an Imiquimod-Induced Mouse Model of Dermatitis. Chen Y et al., 2015, PLoS OneRead more
- The HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin modulates radiosensitivity by downregulating serine/threonine kinase 38 via Sp1 inhibition. Enomoto A et al., 2013 Nov, Eur J CancerRead more