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C/EBP beta antibody

GTX100675
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCEBPB
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Overview

  • Supplier
    GeneTex
  • Product Name
    C/EBP beta antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.05 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1051
  • Target name
    CEBPB
  • Target description
    CCAAT enhancer binding protein beta
  • Target synonyms
    C/EBP-beta, IL6DBP, NF-IL6, TCF5, CCAAT/enhancer-binding protein beta, CCAAT/enhancer binding protein (C/EBP), beta, interleukin 6-dependent DNA-binding protein, nuclear factor NF-IL6, nuclear factor of interleukin 6, transcription factor 5, transcription factor C/EBP beta
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP17676
  • Protein Name
    CCAAT/enhancer-binding protein beta
  • Scientific Description
    The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Hartl L, Roelofs JJTH, Dijk F, et al. C/EBP-Family Redundancy Determines Patient Survival and Lymph Node Involvement in PDAC. Int J Mol Sci. 2023,24(2). doi: 10.3390/ijms24021537
    Read this paper
  • Zhao H, Lu J, Yan T, et al. Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2. Cell Rep. 2022,38(4):110253. doi: 10.1016/j.celrep.2021.110253
    Read this paper
  • Du L, Wang H, Liu F, et al. NSP2 Is Important for Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus to Trigger High Fever-Related COX-2-PGE2 Pathway in Pigs. Front Immunol. 2021,12:657071. doi: 10.3389/fimmu.2021.657071
    Read this paper
  • Bastola S, Pavlyukov MS, Yamashita D, et al. Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy. Nat Commun. 2020,11(1):4660. doi: 10.1038/s41467-020-18189-y
    Read this paper
  • Lin CK, Tseng CK, Liaw CC, et al. Lobohedleolide suppresses hepatitis C virus replication via JNK/c-Jun-C/EBP-mediated down-regulation of cyclooxygenase-2 expression. Sci Rep. 2018,8(1):8676. doi: 10.1038/s41598-018-26999-w
    Read this paper
  • Chen Y, Yan H, Song Z, et al. Downregulation of TNIP1 Expression Leads to Increased Proliferation of Human Keratinocytes and Severer Psoriasis-Like Conditions in an Imiquimod-Induced Mouse Model of Dermatitis. PLoS One. 2015,10(6):e0127957. doi: 10.1371/journal.pone.0127957
    Read this paper
  • Enomoto A, Fukasawa T, Takamatsu N, et al. The HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin modulates radiosensitivity by downregulating serine/threonine kinase 38 via Sp1 inhibition. Eur J Cancer. 2013,49(16):3547-58. doi: 10.1016/j.ejca.2013.06.034
    Read this paper