Bio-Connect

C/EBP beta antibody

GTX100675
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCEBPB
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Overview

  • Supplier
    GeneTex
  • Product Name
    C/EBP beta antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.05 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1051
  • Target name
    CEBPB
  • Target description
    CCAAT enhancer binding protein beta
  • Target synonyms
    C/EBP-beta; CCAAT/enhancer binding protein (C/EBP), beta; CCAAT/enhancer-binding protein beta; IL6DBP; interleukin 6-dependent DNA-binding protein; NF-IL6; nuclear factor NF-IL6; nuclear factor of interleukin 6; TCF5; transcription factor 5; transcription factor C/EBP beta
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP17676
  • Protein Name
    CCAAT/enhancer-binding protein beta
  • Scientific Description
    The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • C/EBP-Family Redundancy Determines Patient Survival and Lymph Node Involvement in PDAC.
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  • Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2. Zhao H et al., 2022 Jan 25, Cell Rep
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  • NSP2 Is Important for Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus to Trigger High Fever-Related COX-2-PGE2 Pathway in Pigs. Du L et al., 2021, Front Immunol
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  • Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy. Bastola S et al., 2020 Sep 16, Nat Commun
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  • Lobohedleolide suppresses hepatitis C virus replication via JNK/c-Jun-C/EBP-mediated down-regulation of cyclooxygenase-2 expression. Lin CK et al., 2018 Jun 6, Sci Rep
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  • Downregulation of TNIP1 Expression Leads to Increased Proliferation of Human Keratinocytes and Severer Psoriasis-Like Conditions in an Imiquimod-Induced Mouse Model of Dermatitis. Chen Y et al., 2015, PLoS One
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  • The HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin modulates radiosensitivity by downregulating serine/threonine kinase 38 via Sp1 inhibition. Enomoto A et al., 2013 Nov, Eur J Cancer
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