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Celastrol (NSC 70931) [34157-83-0]

S1290
Selleck Chemicals
CAS Number34157-83-0
Product group Chemicals
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Celastrol (NSC 70931) [34157-83-0]
  • Delivery Days Customer
    9
  • CAS Number
    34157-83-0
  • Certification
    Research Use Only
  • Scientific Description
    Celastrol (NSC 70931, Tripterine) is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 muM. Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway. Celastrol inhibits dopaminergic neuronal death of Parkinson's disease through activating mitophagy.
  • UNSPSC
    12352200

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