Celastrol (NSC 70931) [34157-83-0]
S1290
CAS Number34157-83-0
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameCelastrol (NSC 70931) [34157-83-0]
- Delivery Days Customer9
- CAS Number34157-83-0
- CertificationResearch Use Only
- Scientific DescriptionCelastrol (NSC 70931, Tripterine) is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 muM. Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway. Celastrol inhibits dopaminergic neuronal death of Parkinson's disease through activating mitophagy.
- UNSPSC12352200