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ProductsBack/Ceritinib dihydrochloride [1380575-43-8]
Ceritinib dihydrochloride [1380575-43-8]

Ceritinib dihydrochloride [1380575-43-8]

T1791L
TargetMol Chemicals
CAS Number1380575-43-8
Product group Chemicals
Estimated Purity99.99%
Molecular Weight631.06
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Ceritinib dihydrochloride
  • Delivery Days Customer
    4
  • CAS Number
    1380575-43-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Ceritinib dihydrochloride
  • Estimated Purity
    99.99%
  • Molecular Formula
    C28H38Cl3N5O3S
  • Molecular Weight
    631.06
  • Scientific Description
    Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable, ATP-competitive inhibitor of ALK tyrosine kinase (IC50 of 200 pM) and also inhibits IGF-1R, InsR, and STK22D [IC50 values of 8, 7, and 23 nM, respectively], demonstrating significant antitumor potency.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.Cl.CC(C)Oc1cc(C2CCNCC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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