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Ceritinib (LDK378) dihydrochloride

M6168
AbMole BioScience
CAS Number1380575-43-8
DownloadDatasheet
Product group Chemicals
Estimated Purity0.9981
Molecular Weight631.06
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Ceritinib (LDK378) dihydrochloride
  • Delivery Days Customer
    9
  • CAS Number
    1380575-43-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    0.9981
  • Molecular Formula
    C28H38Cl3N5O3S
  • Molecular Weight
    631.06
  • Scientific Description
    Ceritinib dihydrochloride (LDK378 dihydrochloride) is potent inhibitor against ALK with IC50 of 0.2 nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.
  • SMILES
    Cl.Cl.CC(C)OC1=C(NC2=NC=C(Cl)C(=N2)NC3=CC=CC=C3[S](=O)(=O)C(C)C)C=C(C)C(=C1)C4CCNCC4
  • UNSPSC
    12352200