BX-795
S1274
CAS Number702675-74-9
Product group Chemicals
Estimated Purity...
Overview
- SupplierSelleck Chemicals
- Product NameBX-795 [702675-74-9]
- Delivery Days Customer9
- CAS Number702675-74-9
- CertificationResearch Use Only
- Estimated Purity...
- Scientific DescriptionBX-795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, 140- and 1600-fold more selective for PDK1 than PKA and PKC in cell-free assays, respectively. Meanwhile, in comparison to GSK3beta more than 100-fold selectivity observed for PDK1. BX-795 modulates autophagy via inhibiting ULK1. BX-795 also is a potent TBK1 inhibitor that blocks both TBK1 and IKKepsilon with IC 50 values of 6 nM and 41 nM, respectively.
- Storage Instruction-80°C
- UNSPSC51202000
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