Bio-Connect

BX-795

S1274
Selleck Chemicals
CAS Number702675-74-9
Product group Chemicals
Estimated Purity...
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    BX-795 [702675-74-9]
  • Delivery Days Customer
    9
  • CAS Number
    702675-74-9
  • Certification
    Research Use Only
  • Estimated Purity
    ...
  • Scientific Description
    BX-795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, 140- and 1600-fold more selective for PDK1 than PKA and PKC in cell-free assays, respectively. Meanwhile, in comparison to GSK3beta more than 100-fold selectivity observed for PDK1. BX-795 modulates autophagy via inhibiting ULK1. BX-795 also is a potent TBK1 inhibitor that blocks both TBK1 and IKKepsilon with IC 50 values of 6 nM and 41 nM, respectively.
  • Storage Instruction
    -80°C
  • UNSPSC
    51202000

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