BX-795 [702675-74-9]
SYN-1026
CAS Number702675-74-9
Product group Chemicals
Estimated Purity>95%
Molecular Weight591.5
Overview
- SupplierSYNkinase
- Product NameBX-795 [702675-74-9]
- Delivery Days Customer10
- CAS Number702675-74-9
- CertificationResearch Use Only
- Estimated Purity>95%
- Molecular FormulaC23H26IN7O2S
- Molecular Weight591.5
- Scientific DescriptionBX795 was initially developed as a PDK1 inhibitor (direct competitive inhibitor IC(50) 11nM for PDK1) and has been shown to be a potent and relatively specific inhibitor of TBK1 and IKK-epsilon. It blocks the phosphorylation, nuclear translocation, and transcriptional activity of interferon regulatory factor 3. BX795 also is a potent inhibitor of cell growth of multiple cancer cell lines with IC(50) values ranging from submicromolar amounts (0.368microM to greater than 450microM. - Chemical. CAS: 702675-74-9. Formula: C23H26IN7O2S. MW: 591.5. BX795 was initially developed as a PDK1 inhibitor (direct competitive inhibitor IC(50) 11nM for PDK1) and has been shown to be a potent and relatively specific inhibitor of TBK1 and IKK-epsilon. It blocks the phosphorylation, nuclear translocation, and transcriptional activity of interferon regulatory factor 3. BX795 also is a potent inhibitor of cell growth of multiple cancer cell lines with IC(50) values ranging from submicromolar amounts (0.368microM to greater than 450microM.
- Storage Instruction2°C to 8°C
- UNSPSC51202000