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CHIR 99021 trihydrochloride

M6594
AbMole BioScience
CAS Number1782235-14-6
Product group Chemicals
Molecular Weight574.72
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    CHIR 99021 trihydrochloride
  • Delivery Days Customer
    9
  • CAS Number
    1782235-14-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C22H18Cl2N8.3HCl
  • Molecular Weight
    574.72
  • Scientific Description
    Laduviglusib (CHIR-99021) trihydrochloride is a potent and selective GSK-3alfa/bèta inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib trihydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib trihydrochloride is also a potent Wnt/bèta-catenin signaling pathway activator.
  • UNSPSC
    12352200

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