Chk2 antibody [2F4]

GeneTex

Chk2 antibody [2F4] - KO/KD, Overexpression Validated

9

WB: 1:1000-1:2000. ICC/IF: 1:50-1:100. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

2F4

1.2 mg/ml

Unconjugated

CHEK2

checkpoint kinase 2

CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, TPDS4, hCds1, serine/threonine-protein kinase Chk2, CHK2 checkpoint homolog, cds1 homolog, checkpoint-like protein CHK2

Mouse

IgG2b

Serine/threonine-protein kinase Chk2

Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on Ser-216, preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at Thr-18 and Ser-20.

-20°C or -80°C,2°C to 8°C

12352203