Chloroquine . diphosphate [50-63-5]
AG-CR1-3721
Overview
- SupplierAdipoGen Life Sciences
- Product NameChloroquine . diphosphate [50-63-5]
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity>98%
- Hazard InformationNon-hazardous,Warning
- Molecular FormulaC18H26ClN3 . 2H3PO4
- Molecular Weight319.9 . 196.0
- Scientific DescriptionChemical. CAS: 50-63-5. Formula: C18H26ClN3 . 2H3PO4. MW: 319.9 . 196.0. Chloroquine is a commonly used antimalarial drug, more toxic than its derivative hydroxychloroquine (Prod. No. AG-CR1-3720). Chloroquine has anti-inflammatory, immunomodulating, anti-infective, antiviral, antithrombotic and metabolic effects. It has anticancer properties, related to their strong antiproliferative, antimutagenic, epigenetic and autophagy inhibiting and apoptosis inducing activities. Chloroquine is used to treat rheumatoid arthritis, systemic lupus erythematosus, antiphospholipid antibody syndrome and Sjoegrens syndrome. Chloroquine interfers with lysosomal activity and autophagy, interacts with membrane stability and alters signaling pathways and transcriptional activity, which can result in inhibition of cytokine production and modulation of certain co-stimulatory molecules. Chloroquine shows antiviral activity against several viruses by inhibiting viral replication and inhibits SARS-CoV-2 viral infection (COVID-19) in vitro. - Chloroquine is a commonly used antimalarial drug, more toxic than its derivative hydroxychloroquine (Prod. No. AG-CR1-3720). Chloroquine has anti-inflammatory, immunomodulating, anti-infective, antiviral, antithrombotic and metabolic effects. It has anticancer properties, related to their strong antiproliferative, antimutagenic, epigenetic and autophagy inhibiting and apoptosis inducing activities. Chloroquine is used to treat rheumatoid arthritis, systemic lupus erythematosus, antiphospholipid antibody syndrome and Sjoegrens syndrome. Chloroquine interfers with lysosomal activity and autophagy, interacts with membrane stability and alters signaling pathways and transcriptional activity, which can result in inhibition of cytokine production and modulation of certain co-stimulatory molecules. Chloroquine shows antiviral activity against several viruses by inhibiting viral replication and inhibits SARS-CoV-2 viral infection (COVID-19) in vitro.
- SMILESClC1=CC=C(C(NC(CCCN(CC)CC)C)=CC=N2)C2=C1.[2 H3PO4]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352200