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Chemical Structure
Chemical Structure
Chemical Structure

Chloroquine . diphosphate [50-63-5]

Research Use Only
AG-CR1-3721
AdipoGen Life Sciences
CAS Number50-63-5
Product group Chemicals
Estimated Purity>98%
Molecular Weight319.9 . 196.0
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Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Chloroquine . diphosphate [50-63-5]
  • Delivery Days Customer
    10
  • CAS Number
    50-63-5
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Warning
  • Molecular Formula
    C18H26ClN3 . 2H3PO4
  • Molecular Weight
    319.9 . 196.0
  • Scientific Description
    Chemical. CAS: 50-63-5. Formula: C18H26ClN3 . 2H3PO4. MW: 319.9 . 196.0. Chloroquine is a commonly used antimalarial drug, more toxic than its derivative hydroxychloroquine (Prod. No. AG-CR1-3720). Chloroquine has anti-inflammatory, immunomodulating, anti-infective, antiviral, antithrombotic and metabolic effects. It has anticancer properties, related to their strong antiproliferative, antimutagenic, epigenetic and autophagy inhibiting and apoptosis inducing activities. Chloroquine is used to treat rheumatoid arthritis, systemic lupus erythematosus, antiphospholipid antibody syndrome and Sjoegrens syndrome. Chloroquine interfers with lysosomal activity and autophagy, interacts with membrane stability and alters signaling pathways and transcriptional activity, which can result in inhibition of cytokine production and modulation of certain co-stimulatory molecules. Chloroquine shows antiviral activity against several viruses by inhibiting viral replication and inhibits SARS-CoV-2 viral infection (COVID-19) in vitro. - Chloroquine is a commonly used antimalarial drug, more toxic than its derivative hydroxychloroquine (Prod. No. AG-CR1-3720). Chloroquine has anti-inflammatory, immunomodulating, anti-infective, antiviral, antithrombotic and metabolic effects. It has anticancer properties, related to their strong antiproliferative, antimutagenic, epigenetic and autophagy inhibiting and apoptosis inducing activities. Chloroquine is used to treat rheumatoid arthritis, systemic lupus erythematosus, antiphospholipid antibody syndrome and Sjoegrens syndrome. Chloroquine interfers with lysosomal activity and autophagy, interacts with membrane stability and alters signaling pathways and transcriptional activity, which can result in inhibition of cytokine production and modulation of certain co-stimulatory molecules. Chloroquine shows antiviral activity against several viruses by inhibiting viral replication and inhibits SARS-CoV-2 viral infection (COVID-19) in vitro.
  • SMILES
    ClC1=CC=C(C(NC(CCCN(CC)CC)C)=CC=N2)C2=C1.[2 H3PO4]
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200