Chroman 1 [1273579-40-0]

MedChem Express

Chroman 1 [1273579-40-0]

10

1273579-40-0

Research Use Only

99.42

C24H28N4O4

436.50

Chroman 1 is a highly potent and selective ROCK inhibitor. Chroman 1 is more potent against ROCK2 (IC50=1 pM) than ROCK1 (IC50=52 pM). Chroman 1 also has inhibitory activity against MRCK, with an IC50 of 150 nM[1][2].

O=C([C@@H]1COC2=CC=C(OC)C=C2C1)NC3=CC=C(C4=CNN=C4)C=C3OCCN(C)C

-20°C,2°C to 8°C

12352200