Chroman 1

MedChem Express

Chroman 1 [1273579-40-0]

10

1273579-40-0

Research Use Only

99.42

C24H28N4O4

436.50

Chroman 1 is a highly potent and selective ROCK inhibitor. Chroman 1 is more potent against ROCK2 ( IC 50 =1 pM) than ROCK1 ( IC 50 =52 pM). Chroman 1 also has inhibitory activity against MRCK , with an IC 50 of 150 nM [1] [2] .

O=C([C@@H]1COC2=CC=C(OC)C=C2C1)NC3=CC=C(C4=CNN=C4)C=C3OCCN(C)C

-20°C,2°C to 8°C

12352200