Chroman 1

AbMole BioScience

Chroman 1

9

1273579-40-0

Research Use Only

436.5

Chroman 1 is a highly potent and selective ROCK inhibitor. Chroman 1 is more potent against ROCK2 (IC50=1 pM) than ROCK1 (IC50=52 pM). Chroman 1 also has inhibitory activity against MRCK, with an IC50 of 150 nM.

COC1=CC=C2OCC(CC2=C1)C(=O)NC3=C(OCCN(C)C)C=C(C=C3)C4=C[NH]N=C4

12352200