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Chromogranin A antibody [LK2H10] (ready-to-use)

GTX73638
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCHGA
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Overview

  • Supplier
    GeneTex
  • Product Name
    Chromogranin A antibody [LK2H10] (ready-to-use)
  • Delivery Days Customer
    9
  • Application Supplier Note
    *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    LK2H10
  • Conjugate
    Unconjugated
  • Gene ID1113
  • Target name
    CHGA
  • Target description
    chromogranin A
  • Target synonyms
    betagranin (N-terminal fragment of chromogranin A); catestatin; CGA; chromofungin; chromogranin-A; parathyroid secretory protein 1; pituitary secretory protein I; SP-I
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP10645
  • Protein Name
    Chromogranin-A
  • Scientific Description
    The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Polyclonal Crypt Genesis and Development of Familial Small Intestinal Neuroendocrine Tumors. Sei Y et al., 2016 Jul, Gastroenterology
    Read more
  • Heparin-binding epidermal growth factor-like growth factor stimulates androgen-independent prostate tumor growth and antagonizes androgen receptor function. Adam RM et al., 2002 Dec, Endocrinology
    Read more