CIS antibody [C2C3], C-term

GeneTex

CIS antibody [C2C3], C-term

9

WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

CISH

cytokine inducible SH2 containing protein

BACTS2; CIS; CIS-1; cytokine-inducible inhibitor of signaling type 1B; cytokine-inducible SH2-containing protein; G18; SOCS; suppressor of cytokine signaling

Rabbit

IgG

Cytokine-inducible SH2-containing protein

The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Human, Rat

-20°C or -80°C,2°C to 8°C

12352203