CK 666

AbMole BioScience

CK 666

9

442633-00-3

Chemical

Research Use Only

C18H17FN2O

296.34

Ck-666 is a cell-permeable inhibitor (IC50=12 uM) of the Arp2/3 complex, which binds to the Arp2/3 complex and stabilizes the inactive state of the complex, preventing the movement of Arp2 and Arp3 subunits into the active filamentous conformation.

CC1=C(CCNC(=O)C2=CC=CC=C2F)C3=C([NH]1)C=CC=C3

12352200