cK-Ras antibody [234-4.2]

GeneTex

cK-Ras antibody [234-4.2]

9

This antibody reacts with cK Ras and vK Ras, and cross-reacts with cH Ras or cN Ras p21s in immunoblotting. For this reason we recommend a sample concentration step prior to immunoblotting; concentrate to 5 μg/ml with 1% gelatin as a stabilizer. For

For IHC-Fr: Use at a concentration of 10 microg/ml. For IHC-P: Use at a concentration of 10 microg/ml. For IP: Use at an assay dependent dilution. For WB: Use at a concentration of 5 microg/ml. Optimal dilutions/concentrations should be determined by the researcher.

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

234-4.2

0.1 mg/ml

Unconjugated

KRAS

KRAS proto-oncogene, GTPase

cellular c-Ki-ras2 proto-oncogene; cellular transforming proto-oncogene; CFC2; c-Ki-ras; c-Ki-ras2; c-Kirsten-ras protein; 'C-K-RAS; C-K-RAS; GTPase KRas; KI-RAS; Kirsten rat sarcoma viral oncogene homolog; Kirsten rat sarcoma viral proto-oncogene; K-Ras; K-Ras 2; K-ras p21 protein; KRAS1; KRAS2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; NS; NS3; OES; oncogene KRAS2; PR310 c-K-ras oncogene; RALD; RASK2; transforming protein p21; v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog

Mouse

IgG2a

GTPase KRas

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]

Human, Mouse, Rat

2°C to 8°C

12352203