
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA005472LA01HU at dilution of 1:100
CLASP2 Antibody
CSB-PA005472LA01HU
ApplicationsImmunoPrecipitation, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCLASP2
Overview
- SupplierCusabio
- Product NameCLASP2 Antibody
- Delivery Days Customer20
- ApplicationsImmunoPrecipitation, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID23122
- Target nameCLASP2
- Target descriptioncytoplasmic linker associated protein 2
- Target synonymsCLIP-associating protein 2; CLIP-associating protein CLASP2; multiple asters (Mast)-like homolog 2; protein Orbit homolog 2
- HostRabbit
- IsotypeIgG
- Protein IDO75122
- Protein NameCLIP-associating protein 2
- Scientific DescriptionMicrotubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161