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CMPD101 [865608-11-3]

T14989
CAS Number865608-11-3
Product group Chemicals
Estimated Purity99.01%
Molecular Weight466.46
Overview
- SupplierTargetMol Chemicals
- Product NameCMPD101 [865608-11-3]
- Delivery Days Customer4
- CAS Number865608-11-3
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameCMPD101
- Estimated Purity99.01%
- Molecular FormulaC24H21F3N6O
- Molecular Weight466.46
- Scientific DescriptionCMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM). Which can be used for the study of heart failure. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCalpha with IC50s of 3.1 microM , 2.3 microM, 1.4 microM and 8.1 microM, respectively.
- Shelf life instruction3 years
- SMILESCn1c(CNc2cccc(c2)C(=O)NCc2ccccc2C(F)(F)F)nnc1-c1ccncc1
- Storage Instruction-20°C
- UNSPSC12352200
References
- Inhibition of prostatic smooth muscle contraction by the inhibitor of G protein-coupled receptor kinase 2/3, CMPD101. Yu Q et al., 2018 Jul 15, Eur J PharmacolRead more